You may want to do some tests to see what you like best. I’m very skeptical, however, that Vuescan or your scanner is capable of physically adjusting the scan time for each individual color CCD channel. Instead, I believe that the scanning software makes the adjustment to the scan data.

Even so, such adjustments may be useful and give you good results.Ī couple of other things to add to what Bart already mentioned is that you may want to save your scans in 16 bit and use either your scanner’s native color space or maybe ProPhoto or aRGB (I’m not sure what’s best for B&W). Also, if you save your scans in Tiff format, be sure that your color space profile is embedded in your file before you open it in ACR, otherwise ACR will assume it is sRGB. I’d also recommend that you do some tests with your Epson scanning software. It may turn out that you like the results, but you won’t know until you do some tests. I use a Minolta scanner and after some tests I found that the Minolta software provided much better results with color negatives than did Vuescan. Vuescan is very capable scanning software with lots of settings te be considered but challenging to master.

I usually scan B&W negatives with a profiled scanner, saved out as inverted high bit full res greyscale TIFF's with gray profile assigned. I always use 10% border to compensate for black or transparent edges of the negative interfering with Vuescan exposure calculations if you don't get the cropping right or using 'maximum' in the crop dialogue.

Vuescan 9.0.21